Friday, November 8^th, 2013, 13:00 h – 18:45 h
Saturday, November 9^th, 2013, 09:00 h – 16:00 h

Center for Technology Europaplatz
Dennewartstr. 25-27
52068 Aachen, Germany

Auditorium

Prof. Dr. Peter Walter
Department of Ophthalmology, University Hospital Aachen
RWTH Aachen University, Medical Faculty
Pauwelsstraße 30
52074 Aachen, Germany
Phone: +49 2 41 / 8 08 -81 91
Fax: +49 2 41 / 8 08 - 20 47
E-Mail: pwalter@ukaachen.de

Congress-Organisation Gerling GmbH
Werftstraße 23
40549 Düsseldorf, Germany
Phone: +49 2 11 / 59 22 44
Fax: +49 2 11 / 59 35 60
E-Mail: info@congresse.de, Internet: www.congresse.de

Friday, November 8^th, 2013, 12:00 h – 18:45 h
Saturday, November 9^th, 2013, 08:30 h – 16:00 h

English

See hotel list on the registration form.

* Trainees must supply a letter of verification as proof of training. The letter has to be sent to the congress organization prior to the meeting.

The attendance fee covers the costs for coffee breaks, lunch, and the conference dinner.

Incl. VAT and excl. foreign transfer fees.

by bank transfer (bank details are quoted on your confirmation and invoice. Please do not transfer money without noting your invoice number!), PayPal or by credit card: VISA, AMERICAN EXPRESS, MASTERCARD

Important notes for participants

The attendance fee covers the costs for coffee breaks, lunch, and the conference dinner. If you register late or on site we cannot guarantee for lunch and participation at the social program.

You are encouraged to apply for the meeting either online, by e-mail or by fax. Cancellation for the symposium has to be made via mail or via fax (+49 211 / 59 35 60) by November 2nd, 2013. In any case an administration fee of EUR 20,– has to be paid. After this dates, no refunds can be made.

Changes, errors and misprints excepted.

The Symposium is registered at the Ärztekammer Nordrhein providing CME points for the German Continuing Medical Education System. Please bring your Bar Code Labels and we will register you for CME point documentation.

An equivalent Certificate of Attendance will be given to you upon on-site registration.

Für deutsche Teilnehmer:

Bitte teilen Sie uns Ihre EF-Nummer (Einheitliche Fortbildungsnummer/Barcode) bereits mit Ihrer Anmeldung mit.

INFORMATIONS FOR SPEAKERS

L = Lectures (15 min presentation incl. discussion)
T = Talk (8 min presentation + 2 min discussion)

Microsoft PowerPoint presentation on CD/DVD/USB-Stick or own notebook.
video codecs: Quicktime 7.6®, Windows Media Player 11.0®

AuditoriumCome together

Welcome notes

Professor Dr. Peter Walter
(Director of the University Eye Clinic Aachen)

Mayor Marcel Philipp
(Mayor of Aachen)

Professor Dr. Ernst Schmachtenberg
(Rector of RWTH Aachen University)

Dr. Michael Lentze
(The Representative of the German Federal Research Agency DFG)

AuditoriumI. Scientific Session

Degenerations of the visual systems – from genes to function

Chair:
Frank Müller (Jülich/D)
Daniel Rathbun (Tübingen/D)

Thomas Theelen, N.M. Bax, C.B. Hoyng (Nijmegen/NL)
Early onset Stargardt disease – a candidate disorder for artificial vision and gene therapy

Carel B. Hoyng, A.I. den Hollander, R.K. Koenekoop (Nijmegen/NL)
Leber Congenital Amaurosis Studies on phenotype and genotype

Sonia Biswas, F. Müller (Jülich/D)
Characterization of the Retinitis Pigmentosa (RP) mouse model, RD-10: A morphological and electrophysical study

Christine Haselier¹, S. Hesse¹, S. Johnen¹, G. Thumann², F. Müller³, P. Walter¹ (¹Aachen/D. ²Genève/CH. ³Jülich/D)
Electrophysiological Differences in Retinae of Wild Type and rd10 Mice influence the Electrical Stimulation Efficiency

Archana Jalligampala^1,2, D. Rathbun¹, E. Zrenner¹ (¹Institute for Ophthalmic Research; Center for Integrative Neuroscience, Tübingen/D. ²Graduate Training Centre of Neuroscience, Tübingen/D)
What is the optimal electrical stimulus for most RGCs?

Daniel L. Rathbun¹, A. Jalligampala^1,2, E. Zrenner¹ (¹Institute for Ophthalmic Research, Center for Integrative Neuroscience, Tübingen/D. ²Graduate Training Centre of Neuroscience, Tübingen/D)
The importance to retinal prostheses of functional diversity across the ganglion cell population

Stephan Hesse, C. Haselier, S. Johnen, P. Walter (Aachen/D)
Different response patterns evoked via epiretinal stimulation in the royal college of surgeons rat

Sarah Rösch^1,2, S. Johnen¹, F. Müller³, C. Pfarrer², P. Walter¹ (¹Aachen/D, ²Hannover/D, ³Jülich/D)
Effects of intravitreal injection of iodoacetic acid and N-methyl-N-nitrosourea on photoreceptor survival in mice

Coffee break in the industrial exhibition

AuditoriumII. Scientific Session

Technology for stimulation of the visual system – from electrodes to systems

Chair:
Gregg Suaning (Sydney/AUS)
Yossi Mandel (Stanford/USA)

Abdel Moneim Marzouk¹, A. Stanitzki², R. Kokozinski¹ (¹Universität Duisburg-Essen, Fachgebiet elektronische Bauelemente und Schaltungen, Duisburg/D. ²Fraunhofer IMS Duisburg/D)
High Frequency Pulse-Density Modulated Switched-Capacitor Based Functional Electrical Stimulation of Retinal Bipolar Cells

Irfan Karagoz¹, G. Sobaci², M. Ozden³ (¹Electrical and Electronics Engineering Department, Gazi University, Ankara/TR. ²Ophthalmology Department, GATA Hospital, Ankara/TR. ³Electrical and Electronics Engineering, Kirikkale University, Kirikkale/TR)
Image processing and neural stimulation methods developed for epiretinal implant systems

Gregg Suaning, N.H. Lovell (Sydney/AUS)
Focal activation of retinal neurons from the supra-choroidal space

Georges Goetz^2,3, R. Smith⁴, X. Lei², T. Kamins², J. Harris², K. Matheison⁵, A. Sher⁴, D. Palanker^1,3 (¹Department of Ophthalmology, Stanford University, Stanford/USA. ²Electrical Engineering, Stanford University, Stanford/USA. ³Hansen Exp. Physics Lab, Stanford University, Stanford/USA. ⁴Santa Cruz Institute for Particle Physics, University of California Santa Cruz/USA. ⁵Institute of Photonics, University of Strathclyde/UK)
Spatial Extent of the Ganglion Cells Response to Subretinal Photovoltaic Stimulation

Günther Zeck, F. Helmhold, M. Eickenscheidt (Tübingen/D)
Spatial sensitivity of subretinal stimulation systems evaluated by flexible microelectrode arrays

Florian Waschkowski¹, A.C. Rieck², C. Brockmann³, T. Laube³, N. Bornfeld³, G. Thumann², P. Walter², W. Mokwa¹ and G. Roessler² (¹Institute for Materials in Electrical Engineering I, RWTH Aachen/D. ²Department of Ophthalmology, University Hospital Aachen/D. ³Essen/D)
Fabrication of Very Large Arrays for Retinal Stimulation

Departure bus transfer to the Conference Dinner

Conference Dinner

AuditoriumIII. Scientific Session

Preclinical tests – from concepts to experimental implantation

Chair:
Gernot Rössler (Aachen/D)
Takashi Fujikado (Osaka/J)

Sandra Johnen¹, F. Meissner², I. Endler², W. Mokwa³, P. Walter¹ (¹Department of Ophthalmology, University Hospital RWTH Aachen/D. ²Fraunhofer Institute for Ceramic Technologies and Systems, Dresden/D. ³Institute of Materials in Electrical Engineering 1, RWTH Aachen University/D)
Biocompatibility of Vertically Aligned Multiwalled Carbon Nanotubes for Nano-Modification of Microelectrode Array Systems

Anne Christine Rieck¹, P. Walter¹, F. Waschkowski², T. Laube³, C. Brockmann⁴, C. Etzkorn¹, W. Mokwa², G. Roessler¹ (¹University Eye-Clinic Aachen, RWTH Aachen/D. ²Institute of Materials in Electrical Engineering 1, RWTH Aachen/D. ³Düsseldorf/D. ⁴Essen/D)
Feasibility of implantation procedures of large multielectrode arrays for epiretinal stimulation

Yossi Mandel^1,2,5, H. Lorach¹, G. Goetz^1,3, D. Lavinsky², P. Huie^1,2, K. Mathieson⁴, L. Wang³, X. Lei³, T. Kamins³, R. Manivanh², J. Harris³, D. Palanker^1,2 (¹Hansen Experimental Physics Laboratory, Stanford University, Stanford/USA. ²Department of Ophthalmology, Stanford University, Stanford/USA. ³Department of Electrical Engineering, Stanford University, Stanford/USA. ⁴Institute of Photonics, University of Strathclyde, Glasgow/UK. ⁵The Mina & Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan/IL)
Photovoltaic Retinal Prosthesis: evaluation in-vivo

Takashi Fujikado¹, M. Kamei², H. Sakaguchi², H. Kanda¹, T. Morimoto¹, K. Nishida², H. Kishima³, T. Maruo³, K. Oosawa⁴, M. Ozawa⁴, K. Nishida² (¹Applied Visual Science, Osaka University Graduate School of Medicine, Osaka/J. ²Ophthalmology, Osaka University Graduate School of Medicine, Osaka/J. ³Neurosurgery, Osaka University Graduate School of Medicine, Osaka/J)
Feasibility of 2nd Generation STS Retinal Prosthesis in dogs

Dov Weinberger¹, R. Gefen², D.R. Prag² (¹Petach Tikva/IL. ²Herzeliya/IL)
In-vivo evaluation of penetrating electrode array implantation technique for artificial retina prosthesis

Coffee break in the industrial exhibition

AuditoriumIV. Scientific Session

Clinical tests – from concepts to products

Chair:
Gislin Dagnelie (Baltimore/USA)
Lauren Ayton (East Melbourne/AUS)

Takeshi Morimoto¹, T. Endo², H. Kanda¹, K. Nishida², T. Fujikado¹ (¹Osaka/JP. ²Suita/JP)
Evaluation of residual retinal preservation by using transcorneal electrical stimulation and optical coherence tomography in patients with advanced retinitis pigmentosa, candidates for retinal prosthesis

Matthias Keserü, G. Richard (Hamburg/D)
Chances and limitations of visual prosthetics – our first experiences with the Argus II epiretinal prosthesis

Eberhart Zrenner¹, D. Besch¹, A. Braun², K.U. Bartz-Schmidt¹, F. Gekeler¹, U. Greppmaier², A. Koitschev³, H. Sachs⁴, K. Stingl¹ (¹Tübingen/D. ²Retina Implant AG, Reutlingen/D. ³Stuttgart/D. ⁴Dresden/D)
Subretinal implant Alpha IMS mediates useful vision in blinding photoreceptor diseases

Stefania Guerra¹, P. Stanga^2,3, F. Merlini¹, J. Sahel^4,5, S. Mohand-Said^4,5, L. daCruz⁶, A. Caspi⁷, R. Greenberg⁷ (¹Second Sight Medical Products, Sàrl, Lausanne/CH. ²Manchester Vision Regeneration (MVR) Lab, Manchester Royal Eye Hospital, Manchester/UK. ³Manchester Academic Health Science Centre and Centre for Ophthalmology and Vision Research, Institute of Human Development, University of Manchester, Manchester/UK. ⁴CHNO des Quinze-Vingts, INSERM-DHOS CIC 503, Paris/F. ⁵Institut de la Vision, CNRS, UMR_7210, Paris/F. ⁶Moorfields Eye Hospital, Moorfields Eye Hospital, London/UK. ⁷Second Sight Medical Products, Inc, Sylmar/USA)
Detection of human faces by blind patients implanted with the Argus® II Retinal Prosthesis System

Gislin Dagnelie¹, H.C. Stronks², M.P. Barry¹ (¹Baltimore/USA. ²Canberra/Aus)
Use of the electrically elicited VEP (EVEP) and ERG (EERG) to probe retinal processing in Argus II recipients

Babac A.E. Mazinani, G. Rössler, H. Schimitzek, P. Walter (Aachen/D)
Comparison of the EPIRET III Prototype and the ARGUS II System after implantation in humans

Gregoire Cosendai¹, A. Istomin², A. Hines², A. Agazaryan², C. Byers², J. Little², B. Mech², D. Zhou², R. Greenberg² (¹Second Sight Medical Products, Sàrl, Lausanne/CH. ²Second Sight Medical Products, Inc, Sylmar/USA)
Argus® II Retinal Implant: long-term study reliability

Lauren N. Ayton¹, C.D. Luu¹, P.J. Allen¹, N.L. Opie¹, J. Villalobos², C.E. Williams², R.H. Guymer, on behalf of the Bionic Vision Australia consortium (¹Centre for Eye Research Australia, The University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne/AUS. ²The Bionics Institute, East Melbourne/AUS)
Stability of a Suprachoroidal Visual Prosthesis

Lunch break in the industrial exhibition

AuditoriumV. Scientific Session

Clinical tests – rehabilitation

Chair:
Michael Scott Evans (Newcastle/UK)

Gislin Dagnelie¹, D. Geruschat² (¹Baltimore/USA. ²Elkins Park/USA)
Update on the Development of a Prosthetic Low Vision Rehabilitation (PLoVR) curriculum

Stefania Guerra¹, F. Anaflous¹, J. Dorn², D. Geruschat³, R. Greenberg² (¹Second Sight Medical Products, Sàrl, Lausanne/CH. ²Second Sight Medical Products, Inc, Sylmar/USA. ³The Maryland School for the Blind, Baltimore/USA)
Elaborating a Rehabilitation Curriculum for Argus® II Retinal Prosthesis System Users

Michael Scott Evans^1,2, Q.C. Vuong¹, P. Degenaar², R. Cheong-Leen³ (¹Newcastle University, Institute of Neuroscience, Newcastle/UK. ²Newcastle University, School of EEE, Newcastle/UK. ³Imperial College, Department of Medicine, Newcastle/UK)
Investigating assistive functions for visual prosthesis with low-vision patients

Gregoire Cosendai¹, P. Walter², A. Augustin³, B. Kirchhof⁴, J. Sahel⁵, L. Da Cruz⁶, S. Rizzo⁷, F. Arevalo⁸ (¹Second Sight Medical Products, Sàrl, Lausanne/ CH. ²Aachen/D. ³Karlsruhe/D. ⁴Köln/D. ⁵CHNO des Quinze-Vingts, INSERM-DHOS CIC 503, Paris/F. ⁶London/UK. ⁷Pisa/I. ⁸Riyadh/KSA)
Safety profile in the Argus® II Retinal Prosthesis System post-market patients

AuditoriumVI. Scientific Session

New ideas – from products back to thoughts – thinking the future

Chair:
Wilfried Mokwa (Aachen/D)
Jong-Mo Seo (Seoul/ROK)

Jong-Mo Seo^1,2, H. Chung¹, S.J. Kim², D.I. Cho², Y.S. Goo³, K.H. Kim⁴, H.H. Koh⁵, (¹Electrical Engineering and Computer Sciences, Seoul/ROK. ²Ophthalmology, Seoul National University Hospital, Seoul/ROK. ³Physiology, Chungbuk National University, Cheongju/ROK. ⁴Biomedical Engineering, Yonsei University, Seoul/ROK. ⁵Electrical Engineering, Chungnam National University, Daejeon/ROK)
Updates of Seoul Artificial Retinal Project

Peter Walter (Aachen/D)
Towards bidirectional retinal stimulators

Stefan Lück, W. Mokwa (Institute of Materials in Electrical Engineering 1, RWTH Aachen, Aachen/D)
Development of penetrating 3-D multi electrode arrays for stimulation of neurons and recording of neuronal activity in the retina

Gernot Rössler¹, D. Klee², W. Mokwa³, B. Sellhaus⁴, B. Mazinani¹, P. Walter¹ (¹Department of Ophthalmology, RWTH Aachen University, Aachen/D. ²Department of Textile and Macromolecular Chemistry, RWTH Aachen University, Aachen/D. ³Department of Materials in Electrical Engineering, RWTH Aachen University, Aachen/D. ⁴Department of Neuropathology, RWTH Aachen University, Aachen/D)
Biocompatibility of Biochemically Modified Surfaces as a Fixation Concept for Epiretinal Stimulator Arrays

Anil Vaidya¹, E. Borgonovi², R.S. Taylor³, J.-A. Sahel⁴, S. Rizzo⁵, P.E. Stanga⁶, A. Kukreja⁷, P. Walter⁸ (¹O-Zone health economics and outcomes research consultancy, Maastricht/NL. ²Public Management & Policy Department, Bocconi University, Milan/I. ³Exeter/UK. ⁴Paris/F. ⁵Pisa/I, ⁶Manchester/UK. ⁷Second Sight Medical Products, Lausanne/CH. ⁸Aachen/D)
The Cost-Effectiveness of the Argus II retinal prosthesis system in Retinitis Pigmentosa patients

General discussion

Farewell

Conference Dinner
in the Kasteel Bloemendal
Bloemendalstraat 150, 6291 CM Vaals
The Netherlands

Pianist and Composer Brigitte Angerhausen and her Band will delight us with her music which has its very own magical touch (www.angerhausen.org/music)

Price per person (incl. dinner and drinks):
Participant included in the attendance fee, but due for notification
Accompanying person EUR 60,–

Bus transfer from the congress venue: 19:30 h
Return: approx. 23:30 h